Multiple aperture synthetic optical coherence tomography for biological tissue imaging

Verification of interferometric synthetic aperture microscopy with optical coherence tomography

Polarimetric Interferometric Synthetic Aperture Microscopy: Vectorial Computed Imaging from Optical Coherence Tomography Data

Interferometric Synthetic Aperture Microscopy (ISAM) obviates the trade-off between depth-of-focus and resolution in interferometric coherence imaging. In this work, ISAM’s quantitative image reconstruction techniques are applied in a vectorial setting, thus admitting polarization-sensitive imaging. ©2007 Optical Society of America OCIS codes: (100.3190) Inverse Problems; (100.6890) Three-dimen...

Automated interferometric synthetic aperture microscopy and computational adaptive optics for improved optical coherence tomography.

In this paper, we introduce an algorithm framework for the automation of interferometric synthetic aperture microscopy (ISAM). Under this framework, common processing steps such as dispersion correction, Fourier domain resampling, and computational adaptive optics aberration correction are carried out as metrics-assisted parameter search problems. We further present the results of this algorith...

Optical coherence tomography imaging of collagenous tissue microstructure

The engineering of new biomaterials requires an in-depth understanding of the structure and function of the native tissues. Optical coherence tomography (OCT) is a non-destructive technique that allows the visualization of the microstructure of biological tissues. The aim of this study was to determine if OCT could be used to identify geometric properties of tendons such as crimp pattern. Fresh...

Imaging thermally damaged tissue by Polarization Sensitive Optical Coherence Tomography.

Polarization Sensitive Optical Coherence Tomography (PS- OCT) was used to image the reduction of birefringence in biological tissue due to thermal damage. Through simultaneous detection of the amplitude of signal fringes in orthogonal polarization states formed by interference of light backscattered from turbid media and a mirror in the reference arm of a Michelson interferometer, changes in th...